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Team Hopes to Use New Technology to Search for ET's




A Johns Hopkins astronomer is a member of a team briefing fellow scientists about plans to use new technology to take advantage of recent, promising ideas on where to search for possible extraterrestrial intelligence in our galaxy.


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Male Enhancement Products Website Offers Reviews of Leading Products
July 05, 2008, MaleEnhancement Institute - Male Enhancement Products Website Offers Reviews of Leading Products
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[NEWS] SCIENCE IN JAPAN: Paper Retraction Puts Focus on Informed Consent Rules
Stung by a front-page newspaper exposé of an alleged lapse in research ethics, officials at the University of Tokyo's Institute of Medical Science are planning to overhaul efforts to educate researchers on ethics rules and tighten internal review and compliance procedures.

Author: Dennis Normile
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[Knee] The effect of quadriceps contraction during weight-bearing on four patellar height indices

The effect of weight-bearing on the height of the patellar using four radiological indices was studied in 25 healthy men using lateral radiographs of the knee in 30° of flexion non-weight-bearing and weight-bearing. The position of the patella was quantified using the Insall-Salvati, the modified Insall-Salvati, the Blackburne-Peel and the Caton indices. The contraction of the quadriceps on weight-bearing resulted in statistically significant proximal displacement of the patella with all four indices studied. The mean Insall-Salvati index was 0.919 (sd 0.063) before and 1.109 (sd 0.042) after weight-bearing (p = 0.001), while the mean modified Insall-Salvati index was 0.734 (sd 0.039) before and 0.896 (sd 0.029) after weight-bearing (p = 0.041). Similarly, the Blackburne-Peel index was 0.691 (sd 0.09) before and 0.807 (sd 0.137) after weight-bearing (p = 0.012). The mean Caton index was 0.861 (sd 0.09) before and 0.976 (sd 0.144) after weight-bearing (p = 0.023).

The effect of quadriceps contraction should be considered in clinical studies where the patellar position indices are reported.

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Imiquimod, An Immune Response Modifier, Is Dependent On The OGF-OGFr Signaling Pathway
Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have discovered that the efficacy of imiquimod, a clinically important immune response modifier with potent antiviral and antitumor activity, is dependent on the Opioid Growth Factor (OGF)-OGF receptor (OGFr) axis for its action.
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[Clinical and Epidemiologic Research] Assessment of the Effect of Visual Impairment on Mortality through Multiple Health Pathways: Structural Equation Modeling

purpose. To estimate the direct effects of self-reported visual impairment (VI) on health, disability, and mortality and to estimate the indirect effects of VI on mortality through health and disability mediators.

methods. The National Health Interview Survey (NHIS) is a population-based annual survey designed to be representative of the U.S. civilian noninstitutionalized population. The National Death Index of 135,581 NHIS adult participants, 18 years of age and older, from 1986 to 1996 provided the mortality linkage through 2002. A generalized linear structural equation model (GSEM) with latent variable was used to estimate the results of a system of equations with various outcomes. Standard errors and test statistics were corrected for weighting, clustering, and stratification.

results. VI affects mortality, when direct adjustment was made for the covariates. Severe VI increases the hazard rate by a factor of 1.28 (95% CI: 1.07–1.53) compared with no VI, and some VI increases the hazard by a factor of 1.13 (95% CI: 1.07–1.20). VI also affects mortality indirectly through self-rated health and disability. The total effects (direct effects plus mediated effects) on the hazard of mortality of severe VI and some VI relative to no VI are hazard ratio (HR) 1.54 (95% CI: 1.28–1.86) and HR 1.23 (95% CI: 1.16–1.31), respectively.

conclusions. In addition to the direct link between VI and mortality, the effects of VI on general health and disability contribute to an increased risk of death. Ignoring the latter may lead to an underestimation of the substantive impact of VI on mortality.

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Homewood News from Johns Hopkins
By dgips@jhu.edu (Debra Gips) - The Johns Hopkins University 2005-2006. - version: v1.5 build A