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[NEWS] SCIENCE AND THE ELECTION: Obama Victory Raises Hopes for New Policies, Bigger Budgets




U.S. scientists hope that last week's elections will usher in an era of sustained, healthy increases in the federal funding of basic research. But with yawning deficits and urgent demands on the federal treasury, those increases may not happen anytime soon.

Authors: Constance Holden, Andrew Lawler, Eli Kintisch, Jeffrey Mervis, Erik Stokstad


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Fessler to Retire as Dean of Education
Ralph Fessler, the inaugural dean of the Johns Hopkins University School of Education and a state and national leader in teacher education, will retire at the end of the 2008-2009 academic year, he announced today.
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Stretch Mark Cream Review Website Provides Cutting-Edge Advice
July 05, 2008, StretchMarkCream.org - Stretch Mark Cream Review Website Provides Cutting-Edge Advice
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[Knee] Reconstruction of the anterior cruciate ligament in patients over 50 years

The records of patients aged 50 years or over who underwent primary reconstruction of the anterior cruciate ligament between 1990 and 2002 were reviewed. There were 35 knees in 34 patients that met the inclusion criteria. The mean age of the patients was 57 years (50 to 66) and the mean clinical follow-up was for 72 months (25 to 173). A total of 23 knees were reconstructed with patellar tendon allograft, and 12 with patellar tendon autograft. The mean pre-operative knee extension was 1° (–5° to 10°) and flexion was 129° (125° to 150°) and at follow-up these values were 0° (–5° to 5°) and 135° (120° to 150°), respectively. Pre-operatively there were 31 knees (89%) with a Lachman grade 2+ or 3+. Post-operatively, 33 knees (94%) were Lachman grade 0 or 1+. The mean pre- and post-operative International Knee Documentation Committee scores were 39 (23 to 72) and 90 (33 to 100) respectively. The mean pre- and post-operative Lysholm scores were 50 (18 to 68) and 92 (28 to 100) respectively and the mean University of California Los Angeles activity scores were 8.5 before injury (4 to 10), 4.3 (3 to 6) after injury and 8.3 (4 to 10) post-operatively. There were three graft failures (8.6%) requiring revision.

We conclude that reconstruction of the anterior cruciate ligament in carefully-selected patients aged 50 years or over can achieve similar results to those in younger patients, with no increased risk of complications.

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Bringing Africa to the Classroom
Organizers offered practical ways for the nearly 200 teachers to move beyond stereotypes about African disease, poverty, and chaos on the one hand, and safari animals and exotic customs on the other.
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Tibotec Begins European Enrollment For Phase 3 Trial Of Telaprevir In HCV Patients Who Failed Prior Treatment
Tibotec BVBA today announced that it has begun enrolling patients in its phase III study of telaprevir (VX-950), an investigational protease inhibitor (PI), in patients with chronic genotype 1 hepatitis C virus (HCV) for whom the current standard treatment has not been successful. Tibotec is managing the global trial, which is being conducted at more than 50 sites in Europe.
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[Biochemistry and Molecular Biology] Sensitization of RPE Cells by {alpha}B-Crystallin siRNA to SAHA-Induced Stage 1 Apoptosis through Abolishing the Association of {alpha}B-Crystallin with HDAC1 in SC35 Speckles

This paper reveals the mechanism underlying anti-apoptotic role of B-crystallin on SC35 speckles in retinal pigment epithelial cells.

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Science
By American Association for the Advancement of Science - Copyright 2008 American Association for the Advancement of Science - version: v1.5 build A