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| • | Johns Hopkins First in R&D Expenditures for 29th Year |
| The Johns Hopkins University performed $1.55 billion in science, medical and engineering research in fiscal year 2007, making it the leading U.S. academic institution in total research and development spending for the 29th year in a row, according to a new National Science Foundation ranking. | |
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| • | Stretch Mark Cream Review Website Provides Cutting-Edge Advice |
| July 05, 2008, StretchMarkCream.org - Stretch Mark Cream Review Website Provides Cutting-Edge Advice | |
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| • | [NEWS] EVOLUTION: Two Sets of Cave Bear DNA Uncover the Bear Facts |
| A paper published online this week helps untangle bear phylogeny by presenting the mitochondrial genome of the extinct cave bear, Ursus spelaeus. Another paper, published last July, also reported the complete mitochondrial DNA of the cave bear as well as that of the extinct American short-faced bear, Arctodus simus. Author: Michael Balter |
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| • | [Knee] Reconstruction of the anterior cruciate ligament in patients over 50 years |
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The records of patients aged 50 years or over who underwent primary reconstruction of the anterior cruciate ligament between 1990 and 2002 were reviewed. There were 35 knees in 34 patients that met the inclusion criteria. The mean age of the patients was 57 years (50 to 66) and the mean clinical follow-up was for 72 months (25 to 173). A total of 23 knees were reconstructed with patellar tendon allograft, and 12 with patellar tendon autograft. The mean pre-operative knee extension was 1° (–5° to 10°) and flexion was 129° (125° to 150°) and at follow-up these values were 0° (–5° to 5°) and 135° (120° to 150°), respectively. Pre-operatively there were 31 knees (89%) with a Lachman grade 2+ or 3+. Post-operatively, 33 knees (94%) were Lachman grade 0 or 1+. The mean pre- and post-operative International Knee Documentation Committee scores were 39 (23 to 72) and 90 (33 to 100) respectively. The mean pre- and post-operative Lysholm scores were 50 (18 to 68) and 92 (28 to 100) respectively and the mean University of California Los Angeles activity scores were 8.5 before injury (4 to 10), 4.3 (3 to 6) after injury and 8.3 (4 to 10) post-operatively. There were three graft failures (8.6%) requiring revision. We conclude that reconstruction of the anterior cruciate ligament in carefully-selected patients aged 50 years or over can achieve similar results to those in younger patients, with no increased risk of complications. |
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| • | Organ And Cell Culture Methods Featured In Cold Spring Harbor Protocols |
| Understanding the function of organs like the brain, kidney, and reproductive tissues requires experimental systems that allow for the study and manipulation of developing cells and tissues in the laboratory. This month's issue of Cold Spring Harbor Protocols (http://www.cshprotocols.org/TOCs/toc11_08. | |
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| • | [Biochemistry and Molecular Biology] Sensitization of RPE Cells by {alpha}B-Crystallin siRNA to SAHA-Induced Stage 1 Apoptosis through Abolishing the Association of {alpha}B-Crystallin with HDAC1 in SC35 Speckles |
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This paper reveals the mechanism underlying anti-apoptotic role of B-crystallin on SC35 speckles in retinal pigment epithelial cells. |
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By American Association for the Advancement of Science - Copyright 2008 American Association for the Advancement of Science - version: v1.5 build A